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Oracle findings and outcome history for A Study to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD) (NCT05811351).

Runs
5
Findings
5
Latest Run
Apr 6, 2026, 2:57 PM
All Oracle Findings

Every stored oracle finding for this trial, including pending, dismissed, rejected, superseded, and accepted items.

NO_DECISIONDismissed100% confidenceGrok 4.20 (xAI)

Will the results be positive?

Trial completed per status, but no public readout, topline results, or interpretation found in searches as of April 2026. ClinicalTrials.gov and other sites show no results posted; recent articles describe trial as ongoing or evaluating. Lacks clear positive/negative framing specific to this trial.

Found Apr 6, 2026, 2:58 PMReviewed Apr 6, 2026, 3:00 PM
NO_DECISIONDismissed85% confidenceGrok 4.20 (xAI)

Will the results be positive?

NCT05811351 (PARASOL Phase 2) is listed as completed (primary est. Feb 2026; actual enrollment 305) with results not yet posted on ClinicalTrials.gov or sponsor sites. No public top-line, press release, or journal article provides a clear positive/negative interpretation of the primary GA lesion growth endpoint for this exact trial. Phase 1 data showed safety and numeric slowing in high-dose cohort but is not trial-specific to this Phase 2.

Found Apr 6, 2026, 2:09 PMReviewed Apr 6, 2026, 2:19 PM
NO_DECISIONDismissed80% confidencemanual-chat-review

Will the results be positive?

ClinicalTrials.gov lists this study as completed but without posted results, so there is no clear public trial-specific basis yet to call the readout positive or negative.

Found Apr 4, 2026, 8:54 PMReviewed Apr 4, 2026, 10:32 PM
NO_DECISIONDismissed94% confidenceGPT-5.4 (OpenAI)

Will the results be positive?

No trial-specific Phase 2 public readout was found. ClinicalTrials.gov shows NCT05811351 completed with "No Results Posted," and a 2026 retina pipeline review still describes PARASOL as being evaluated rather than reporting outcome data. That is insufficient to call the trial positive or negative.

Found Apr 3, 2026, 4:08 PMReviewed Apr 3, 2026, 4:47 PM
NO_DECISIONDismissed92% confidenceGPT-5.4 (OpenAI)

Will the results be positive?

No clear public efficacy readout was found for this exact Phase 2 trial. ClinicalTrials.gov shows NCT05811351 with no results posted, and Janssen’s PARASOL page describes the study design/status without any trial-specific outcome interpretation. That is insufficient to label the readout positive or negative.

Found Apr 1, 2026, 7:12 PMReviewed Apr 1, 2026, 7:16 PM
Outcome History

Public history of accepted oracle reviews and recorded outcome changes for this trial.

No oracle outcome history is available for this trial yet.