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Oracle Runs

Oracle findings and outcome history for A Proof-of-concept Study of Lunsekimig Compared With Placebo in Adults With Chronic Rhinosinusitis With Nasal Polyps (NCT06454240).

Runs
4
Findings
4
Latest Run
Apr 6, 2026, 2:08 PM
All Oracle Findings

Every stored oracle finding for this trial, including pending, dismissed, rejected, superseded, and accepted items.

NO_DECISIONDismissed90% confidenceGrok 4.20 (xAI)

Will the results be positive?

Trial is active, not recruiting; primary completion Jan 2026. No public readout or efficacy results available. Sanofi notes readout anticipated in 2026. No positive/negative framing found for this exact Phase 2 CRSwNP trial.

Found Apr 6, 2026, 2:08 PMReviewed Apr 6, 2026, 2:19 PM
ClinicalTrialsclinicaltrials.gov
NCT06454240 | A Proof-of-concept Study of Lunsekimig Compared With Placebo in Adults With Chronic Rhinosinusitis With Nasal Polyps
Current Status: Active Not Recruiting. Estimated Primary Completion: 2026-01-29. No results posted.
Web Searchsanofi.comApr 15, 2025, 12:00 AM
Press Release: Sanofi's respiratory pipeline advances with new data
The readout of the phase 2 study in patients with chronic rhinosinusitis with nasal polyps (NCT06454240) is anticipated in 2026.
NO_DECISIONDismissed90% confidencemanual-chat-review

Will the results be positive?

ClinicalTrials.gov still lists this study as active not recruiting with no posted results, so there is not yet a clear public positive or negative trial readout.

Found Apr 4, 2026, 8:54 PMReviewed Apr 4, 2026, 10:32 PM
ClinicalTrialsclinicaltrials.govFeb 5, 2026, 12:00 AM
Study Details | NCT06454240 | ClinicalTrials.gov
ClinicalTrials.gov lists active not recruiting; primary completion 2026-01-29; hasResults=false on the latest posted update.
NO_DECISIONDismissed90% confidenceGPT-5.4 (OpenAI)

Will the results be positive?

No clear trial-specific efficacy readout is publicly available. Recent sources still describe NCT06454240 as ongoing/active and note no results posted, while Sanofi only said the readout was anticipated in 2026. Without a public positive/negative interpretation for this exact Phase 2 trial, outcome cannot be classified.

Found Apr 3, 2026, 4:03 PMReviewed Apr 3, 2026, 4:47 PM
Web Searchcdek.pharmacy.purdue.eduNov 3, 2024, 12:00 AM
Trial | NCT06454240
Trial page for NCT06454240 states 'No Results Posted' and shows study results section as empty for this Phase 2 lunsekimig CRSwNP trial.
Web Searchfdaaa.trialstracker.netAug 3, 2025, 12:00 AM
NCT06454240: An ongoing trial by Sanofi
FDAAA TrialTracker lists NCT06454240 as 'an ongoing trial by Sanofi,' indicating no completed public readout was identified there.
Sponsorsanofi.comApr 15, 2025, 5:00 AM
Sanofi’s respiratory pipeline advances with new data in asthma and plans for new clinical studies in COPD
Sanofi said the phase 2 study in CRSwNP (NCT06454240) had a readout 'anticipated in 2026,' which is schedule guidance, not a positive or negative trial result.
NO_DECISIONDismissed94% confidenceGPT-5.4 (OpenAI)

Will the results be positive?

No trial-specific efficacy readout was found. Sanofi said the NCT06454240 readout was anticipated in 2026/H1 2026, and an as-of March 2026 tracker still shows the study as ongoing with no results reported. Without a public readout, the outcome cannot be framed positive or negative.

Found Apr 1, 2026, 6:40 PMReviewed Apr 1, 2026, 6:46 PM
Sponsorsanofi.comApr 15, 2025, 5:00 AM
Sanofi respiratory pipeline advances with new data in asthma and plans for new clinical studies in COPD
Sanofi said the Phase 2 CRSwNP study NCT06454240 readout is anticipated in 2026, indicating no public result at that time.
Sponsorsanofi.comDec 16, 2025, 12:00 AM
Sanofi Year-end late-stage pipeline review presentation
Sanofi’s Dec. 2025 pipeline deck lists lunsekimig CRSwNP with Phase 2 study readout in H1 2026, still forward-looking rather than reported data.
Web Searchfdaaa.trialstracker.netMar 18, 2026, 12:00 AM
NCT06454240: An ongoing trial by Sanofi
Tracker page for NCT06454240 shows Results Status: Ongoing; Actual reporting date: None; ClinicalTrials.gov last checked March 10, 2026.
Outcome History

Public history of accepted oracle reviews and recorded outcome changes for this trial.

No oracle outcome history is available for this trial yet.