Oracle Runs

Will the results be positive?

No public readout available for NCT05348785 (LUMA Phase 2). Trial active, enrollment complete, primary completion Feb 2026, data expected mid-2026 per sponsor updates. Only baseline analyses presented; no efficacy or safety results released.

Will the results be positive?

Trial (LUMA, NCT05348785) is active/not recruiting with primary completion Feb 2026; no topline efficacy results posted on clinicaltrials.gov or in sponsor updates. Recent sources only note ongoing status, digital endpoint validation from baseline data, and expected mid-2026 readout. No framing of positive/negative outcome for primary MDS-UPDRS endpoint.

Will the results be positive?

ClinicalTrials.gov still lists this study as active not recruiting with no posted results, so there is not yet a clear public positive or negative trial readout.

Will the results be positive?

No trial-specific Phase 2 efficacy readout is public yet. ClinicalTrials.gov still lists NCT05348785 as active, not recruiting, with estimated primary completion on 2026-02-25, and Denali said the LUMA Phase 2b data readout is expected in mid-2026. Without results, direction cannot be classified.

Will the results be positive?

No trial-specific efficacy readout was found. The most recent sponsor update says the Phase 2b LUMA data readout is expected in mid-2026, and an independent trial-tracking source lists NCT05348785 as ongoing with no actual results reporting date. Without a public readout, direction cannot be classified.