GSK4527226 in Early Alzheimer's Disease

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Primary Completion
9/30/26
Study Completion
11/23/26
Sponsor
GlaxoSmithKline
$GSK
Type
Phase 2
Trial Status
Active Not Recruiting
Trial Size
367
Volume
$603
NCT
NCT06079190
Trial Description
Phase 2 randomized, double-blind, placebo-controlled, 3-arm multicenter study evaluating intravenous GSK4527226 in participants with early Alzheimer's disease, including MCI and mild dementia due to AD. The study compares two dose levels of GSK4527226 versus placebo, with the primary efficacy endpoint based on change from baseline in CDR-SB across Weeks 52, 64, and 76.