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Ascentage Pharma

Pipeline7 assets

  • OlverembatinibHQP1351 / BCR-ABL / small molecule TKI / Oncology
    CML-CP/AP with T315I; CML-CP resistant/intolerant to 1st/2nd gen TKIsMarketedApproved in ChinaChinaCMLPhase 3 registrationalOngoing; POLARIS-2GlobalFirst-line Ph+ ALLPhase 3 registrationalOngoing; POLARIS-1Global
  • LisaftoclaxAPG-2575 / Bcl-2 / small molecule inhibitor / Oncology
    CLL/SLL after systemic therapy including BTK inhibitorsMarketedApproved in China 2025ChinaCLL/SLL after BTK inhibitorsPhase 3 registrationalOngoing; GLORA; +BTK inhibitorGlobalFirst-line CLL/SLLPhase 3 registrationalOngoing; GLORA-2; +acalabrutinibGlobal
  • APG-2449APG-2449 / FAK/ALK/ROS1 / small molecule inhibitor / Oncology
    ALK-positive advanced or locally advanced NSCLC, treatment-naivePhase 3 registrationalOngoing; CDE-clearedChinaNSCLC resistant/intolerant to 2nd generation ALK TKIsPhase 3 registrationalOngoing; CDE-clearedChinaPlatinum-resistant ovarian cancerPhase 1b/2Ongoing; +liposomal doxorubicin
  • AlrizomadlinAPG-115 / MDM2-p53 / small molecule inhibitor / Oncology
    Unresectable/metastatic melanoma and other advanced solid tumorsPhase 1b/2Ongoing; monotherapy or +pembrolizumabUnited StatesAustraliaR/R T-PLL or NHLPhase 2aOngoing; monotherapy or +lisaftoclaxUnited StatesAustraliaSalivary gland cancerPhase 2Collaborative research study
  • PelcitoclaxAPG-1252 / Bcl-2/Bcl-xL / small molecule inhibitor / Oncology
    EGFR-mutant NSCLCPhase 1bOngoing; +osimertinibChinaR/R NHLPhase 1b/2OngoingChinaRecurrent ovarian and endometrial cancersPhase 1Ongoing; +cobimetinib
  • APG-5918APG-5918 / EED/PRC2 / small molecule inhibitor / Oncology; Hematology
    Advanced solid tumors and hematologic malignanciesPhase 1OngoingChinaUnited StatesAnemia-related indicationsPhase 1OngoingChina
  • APG-3288APG-3288 / BTK / PROTAC degrader / Oncology
    R/R B-cell malignanciesPhase 1IND cleared; planned/initiating in 2026United StatesChina

Latest news16 items

All news

Ascentage Pharma Presents Multiple Clinical Updates at EHA2026 Congress

Poster presentations from ongoing clinical trials of two core assets, olverembatinib and lisaftoclax, highlight global innovation capabilities in hematologic malignancies ROCKVILLE, Md. and SUZHOU, China, June 14, 2026 (GLOBE NEWSWIRE) -- Ascentage Pharma Group International (NASDAQ: AAPG; HKEX:

Presentation / Abstract • Phase 3EHA2026 poster presentations Thu, Jun 11, 2026

Ascentage Pharma Presents Data on Olverembatinib in CML-LBP and Ph+ BCP-ALL at ASCO 2026

ROCKVILLE, Md. and SUZHOU, China, May 31, 2026 (GLOBE NEWSWIRE) -- Ascentage Pharma Group International (NASDAQ: AAPG; HKEX: 6855), a global, commercial-stage, integrated biopharmaceutical company engaged in the discovery, development and commercialization of novel therapies to address unmet

Presentation / Abstract • Phase 1ASCO rapid oral presentation Sun, May 31, 2026

Ascentage Pharma Releases Latest Clinical Data from Multiple Trials at ASCO 2026

ROCKVILLE, Md. and SUZHOU, China, May 21, 2026 (GLOBE NEWSWIRE) -- Ascentage Pharma Group International (NASDAQ: AAPG; HKEX: 6855), a global, commercial-stage, integrated biopharmaceutical company engaged in the discovery, development and commercialization of novel, differentiated therapies to

Presentation / Abstract • Phase 3ASCO oral presentation Sat, May 30, 2026, 8:00 AM CT

Ascentage Pharma to Present 17 Clinical Advances at 2026 European Hematology Association Congress

ROCKVILLE, Md. and SUZHOU, China, May 12, 2026 (GLOBE NEWSWIRE) -- Ascentage Pharma Group International (NASDAQ: AAPG; HKEX: 6855), a global, integrated biopharmaceutical company engaged in the discovery, development and commercialization of innovative therapies for cancers and other diseases,

Presentation / Abstract • Phase 3EHA poster presentations Sat, Jun 13, 2026, 6:45 PM CEST

Ascentage Pharma to Participate in Three Upcoming Investor Conferences

ROCKVILLE, Md. and SUZHOU, China, May 12, 2026 (GLOBE NEWSWIRE) -- Ascentage Pharma Group International (NASDAQ: AAPG; HKEX: 6855) (“ Ascentage Pharma ” or the “ Company ”), a global, commercial stage, integrated biopharmaceutical company engaged in the discovery, development and commercialization

Ascentage Pharma to Participate in Three Upcoming Investor Conferences

ROCKVILLE, Md. and SUZHOU, China, Feb. 23, 2026 (GLOBE NEWSWIRE) -- Ascentage Pharma Group International (NASDAQ: AAPG; HKEX: 6855) (“ Ascentage Pharma ” or the “ Company ”), a global, commercial stage, integrated biopharmaceutical company engaged in the discovery, development and commercialization

Ascentage Pharma • Endpoint Arena