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AC Immune

Pipeline6 assets

  • ACI-35.030JNJ-2056; JNJ-64042056 / phosphorylated Tau (pTau) / active immunotherapy / neurodegenerative diseases
    preclinical Alzheimer's diseasePhase 2bongoing
  • ACI-24.060amyloid beta (Abeta) / active immunotherapy / neurodegenerative diseases
    Alzheimer's diseasePhase 2ongoingAlzheimer's disease in Down syndromePhase 2ongoing
  • ACI-7104.056alpha-synuclein (a-syn) / active immunotherapy / neurodegenerative diseases
    Parkinson's diseasePhase 2ongoing
  • ACI-19764NLRP3 inflammasome / small molecule inhibitor / neuroinflammation
    neuro-inflammationPhase 1ongoing
  • Morphomer TauTau / small molecule / neurodegenerative diseases
    Alzheimer's diseasePreclinicalIND-enabling studies planned
  • Morphomer a-synalpha-synuclein (a-syn) / small molecule / neurodegenerative diseases
    Parkinson's diseasePreclinicalreadiness to initiate IND-enabling studies

Latest news14 items

All news

AC Immune Announces Positive Preliminary Phase 1 Data for NLRP3 Inhibitor ACI-19764

AC Immune Announces Positive Preliminary Phase 1 Data for NLRP3 Inhibitor ACI-19764 ACI-19764 is an orally available inhibitor of the NLRP3 inflammasome Preliminary data showed ACI-19764 was safe and well tolerated across single and multiple ascending dose cohorts with confirmed CSF penetration

Interim Data • Phase 1Interim data Thu, Aug 20, 2026

AC Immune First Half 2026 Financial and Corporate Update

AC Immune First Half 2026 Financial and Corporate Update Focused portfolio of wholly-owned programs approach near-term clinical catalysts as partnered programs generate milestone payments Key advances across pipeline, with further near-term clinical results anticipated for H2 2026 Phase 2 VacSYn

AC Immune to Showcase Neurodegenerative Disease Pipeline with Three Presentations at AAIC® 2026

AC Immune to Showcase Neurodegenerative Disease Pipeline with Three Presentations at AAIC ® 2026 Lausanne, Switzerland, July 7, 2026 -- AC Immune SA (NASDAQ: ACIU), a clinical-stage biopharmaceutical company pioneering precision therapeutics for neurodegenerative diseases, today announces three

Presentation / AbstractAAIC poster presentation Sun, Jul 12, 2026, 7:30 AM BST

AC Immune Announces Retirement of CEO Dr Andrea Pfeifer at Upcoming AGM

AC Immune Announces Retirement of CEO Dr Andrea Pfeifer at Upcoming AGM Co-founder and CEO, Dr Andrea Pfeifer, to retire after a distinguished 23-year tenure Board Chair, Martin Zügel, MD, to be appointed interim CEO Dr Pfeifer to serve as an Advisor and Honorary Chair of the Board of

AC Immune First Quarter 2026 Financial and Corporate Updates

AC Immune First Quarter 2026 Financial and Corporate Updates Dosed first subjects in Phase 1 trial of brain-penetrant small molecule NLRP3 inhibitor ACI-19764 with SAD/MAD results in healthy volunteers expected in H2 2026 Initiated final cohort, AD4, in ABATE Phase 1b/2 trial of ACI-24 to treat

Trial Start • Phase 1

AC Immune Reports Full Year 2025 Financial Results and Provides a Corporate Update

AC Immune Reports Full Year 2025 Financial Results and Provides a Corporate Update Phase 2 interim results suggest treatment with active immunotherapy ACI-7104 may slow the progression of Parkinson’s disease NLRP3 inhibitor ACI-19764 Phase 1 trial initiated with first participants dosed Approaching

Interim Data • Phase 2
AC Immune • Endpoint Arena