zolbetuximabIMAB362 / VYLOY / Claudin 18.2 / Antibody / Oncology Gastric and gastroesophageal junction adenocarcinoma, combo with pembrolizumab and chemotherapyFiledEuropeJapan
gilteritinibASP2215 / XOSPATA / FLT3 / Small molecule / Oncology Newly diagnosed acute myeloid leukemia with high intensity induction chemotherapyPhase 3Post-chemotherapy maintenance acute myeloid leukemiaPhase 3Post-hematopoietic stem cell transplant maintenance acute myeloid leukemiaPhase 3
Cisplatin-eligible muscle-invasive bladder cancer, combo with pembrolizumabFiledEuropeUSCisplatin-ineligible muscle-invasive bladder cancer, combo with pembrolizumabFiledEuropeJapanBladder-sparing muscle-invasive bladder cancer, combo with pembrolizumabPhase 2
fezolinetantESN364 / VEOZAH / NK3 receptor / Small molecule / Women's Health Vasomotor symptoms due to menopausePhase 3ChinaVasomotor symptoms in breast cancer patients on adjuvant endocrine therapyPhase 2
Pompe diseasePhase 1
ASP2957ASP2957 / MTM1 gene replacement / Gene therapy (AAV-based gene therapy) / Genetic Regulation X-linked myotubular myopathyPhase 1
setidegrasibKRAS G12D / Small molecule degrader / Targeted Protein Degradation Pancreatic ductal adenocarcinomaPhase 3
ASP7317ASP7317 / Retinal pigment epithelial cells / Cell therapy / Ophthalmology Geographic atrophy secondary to age-related macular degenerationPhase 1
ASP1002ASP1002 / Claudin 4/CD137 / T-cell engager bispecific antibody / Oncology Gastric and gastroesophageal junction adenocarcinoma; pancreatic adenocarcinomaPhase 1
ASP5834ASP5834 / Pan-KRAS / Small molecule degrader / Oncology CancerPhase 1
VIR-5500VIR-5500 / PSMA/CD3 / T-cell engager / Oncology Prostate cancerPhase 1
ASP2998ASP2998 / TROP2 / Antibody-drug conjugate (ADC) / Oncology CancerPhase 1
ASP2138ASP2138 / Claudin 18.2/CD3 / T-cell engager bispecific antibody / Oncology CancerPhase 2
ASP546CASP546C / Claudin 18.2 / Antibody-drug conjugate (ADC) / Oncology CancerPhase 2Europe
Prostate cancerPhase 2
mirabegronYM178 / Beta-3 receptor / Small molecule / Urology Neurogenic detrusor overactivity in pediatric patients aged 6 months to less than 3 yearsPhase 3Europe
roxadustatASP1517/FG-4592 / HIF-PH / Small molecule / Nephrology Anemia associated with chronic kidney disease in pediatric patientsPhase 3Europe
Intraoperative ureter visualization for minimally invasive and open abdominopelvic surgeriesPhase 3
