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Arrowhead Pharmaceuticals, Inc.

Pipeline18 assets

  • PlozasiranARO-APOC3 / REDEMPLO / APOC3 / RNAi therapeutic / Cardiometabolic
    Familial chylomicronemia syndromeIn MarketSevere hypertriglyceridemiaPhase 3ActiveHypertriglyceridemiaPhase 3Active
  • ZodasiranARO-ANG3 / ANGPTL3 / RNAi therapeutic / Cardiometabolic
    Homozygous familial hypercholesterolemiaPhase 3Recruiting
  • OlpasiranAMG 890; ARO-LPA / LPA / RNAi therapeutic / Cardiovascular disease
    Elevated lipoprotein(a)/cardiovascular riskPhase 3Recruiting/Active
  • GSK4532990ARO-HSD / HSD17B13 / RNAi therapeutic / Liver disease
    MASH/NASHPhase 2Recruiting
  • ARO-PNPLA3JNJ-75220795 / PNPLA3 / RNAi therapeutic / Liver disease
    MASH/NASHPhase 1
  • ARO-INHBEINHBE/Activin E / RNAi therapeutic / Obesity/metabolic disease
    Obesity with or without type 2 diabetesPhase 1
  • ARO-ALK7ACVR1C/ALK7 / RNAi therapeutic / Obesity/metabolic disease
    Obesity with or without type 2 diabetesPhase 1Recruiting
  • ARO-MAPTMAPT/tau / RNAi therapeutic / CNS
    Alzheimer's diseasePhase 1Recruiting
  • ARO-ATXN2ATXN2 / RNAi therapeutic / CNS
    Spinocerebellar ataxia 2Phase 1
  • SRP-1005ARO-HTT / HTT / siRNA therapeutic / CNS
    Huntington's diseasePhase 1
  • ARO-RAGERAGE / RNAi therapeutic / Pulmonary
    Inflammatory pulmonary diseasesPhase 2Active
  • ARO-MMP7MMP7 / RNAi therapeutic / Pulmonary
    Idiopathic pulmonary fibrosisPhase 1
  • FazirsiranTAK-999; ARO-AAT / Z-AAT / RNAi therapeutic / Liver disease
    Alpha-1 antitrypsin deficiency-associated liver diseasePhase 3Recruiting
  • ARO-HBVJNJ-3989; JNJ-73763989 / HBV gene products / RNAi therapeutic / Infectious disease
    Chronic hepatitis BPhase 2
  • ARO-DUX4DUX4 / RNAi therapeutic / Muscular disease
    Facioscapulohumeral muscular dystrophyPhase 2
  • ARO-DM1DMPK mRNA / RNAi therapeutic / Muscular disease
    Myotonic dystrophy type 1Phase 2Recruiting
  • ARO-C3Complement component 3 / RNAi therapeutic / Complement mediated disease
    Complement-mediated renal diseasePhase 1RecruitingC3 glomerulopathyPhase 1RecruitingIgA nephropathyPhase 1Recruiting
  • ARO-CFBComplement factor B / RNAi therapeutic / Complement mediated disease
    Complement mediated diseasePhase 1

Latest news20 items

All news

Arrowhead Pharmaceuticals to Present New Clinical Data at the European Society of Cardiology Congress

- Detailed results from the Phase 3 SHASTA-3 and SHASTA-4 Studies of Plozasiran in Patients with Severe Hypertriglyceridemia will be presented as a HOT LINE Late-Breaking Science Session on August 30, 2026 - - Arrowhead will host a webcast to review ESC data and Q&A on August 31, 2026 - PASADENA,

Presentation / Abstract • Phase 3ESC Late-Breaking Science Session Sun, Aug 30, 2026, 5:30 PM CEST

Arrowhead Pharmaceuticals Reports Fiscal 2026 Third Quarter Results

- Conference Call and Webcast Today, August 4, 2026, at 4:30 p.m. ET PASADENA, Calif. --(BUSINESS WIRE)--Aug. 4, 2026-- Arrowhead Pharmaceuticals, Inc. (NASDAQ: ARWR) today announced financial results for its fiscal 2026 third quarter ended June 30, 2026.

Presentation / Abstract • Phase 3ESC Congress Hot Line Late Breaker presentation Sun, Aug 30, 2026

Arrowhead Pharmaceuticals Acquires FDA Priority Review Voucher

- Voucher to be used to accelerate review of a planned sNDA for plozasiran in severe hypertriglyceridemia PASADENA, Calif. --(BUSINESS WIRE)--Aug. 4, 2026-- Arrowhead Pharmaceuticals, Inc. (NASDAQ: ARWR) today announced that it has signed an agreement with an undisclosed third party to acquire a

Arrowhead Pharmaceuticals Completes Enrollment in Global Phase 3 YOSEMITE Study of Zodasiran for the Treatment of Homozygous Familial Hypercholesterolemia

- Study completion anticipated in mid-2027 PASADENA, Calif. --(BUSINESS WIRE)--Jul. 27, 2026-- Arrowhead Pharmaceuticals, Inc. (NASDAQ: ARWR) today announced that it has completed enrollment in the global Phase 3 YOSEMITE clinical trial of zodasiran, the company’s investigational RNA interference

Enrollment • Phase 3Enrollment milestone Mon, Jul 27, 2026

Arrowhead Pharmaceuticals Reports Topline Results from Phase 3 SHASTA-3 and SHASTA-4 Studies of Plozasiran in Patients with Severe Hypertriglyceridemia

Deep, durable, and consistent median triglyceride reductions of 79% and 81% from baseline in SHASTA -3 and SHASTA -4, respectively Statistically significant reduction in acute pancreatitis events versus placebo across the entire sHTG study population, with an unprecedented 100% event reduction in

Trial Results • Phase 3ESC Late Breaker presentation Sun, Aug 30, 2026, 5:30 PM CEST

Arrowhead Pharmaceuticals to Webcast Fiscal 2026 Third Quarter Results

PASADENA, Calif. --(BUSINESS WIRE)--Jul. 21, 2026-- Arrowhead Pharmaceuticals, Inc. (NASDAQ: ARWR) today announced that it will host a webcast and conference call on August 4, 2026, at 4:30 p.m. ET to discuss its financial results for the fiscal 2026 third quarter ended June 30, 2026.

Arrowhead Pharmaceuticals to Participate in Upcoming June 2026 Events

PASADENA, Calif. --(BUSINESS WIRE)--Jun. 2, 2026-- Arrowhead Pharmaceuticals, Inc. (NASDAQ: ARWR) today announced that it is scheduled to participate in the following upcoming events: 2026 Jefferies Global Healthcare Conference – June 2-4, 2026 Type: Fireside Chat Presentation Date/Time: June 3,

Arrowhead Pharmaceuticals Presents New Clinical Data on RNAi-based Obesity and MASH Candidate ARO-INHBE at EASL 2026

- Targeting Activin E may represent a novel therapeutic strategy for metabolic dysfunction-associated steatohepatitis (MASH) and obesity‑related metabolic dysfunction - ARO-INHBE produced meaningful reductions in liver fat content as a monotherapy or in combination with low-dose tirzepatide in

Presentation / Abstract • Phase 1/2EASL 2026 poster presentation Wed, May 27, 2026

Arrowhead Pharmaceuticals Presents New Positive Clinical Cardiometabolic Data at the 94th European Atherosclerosis Society (EAS) Congress

- New data support potential use of plozasiran without dose adjustment in patients with moderate-to-severe renal or moderate hepatic impairment - Case report suggests that preconception exposure to plozasiran may be associated with sustained lowering of fasting triglyceride levels throughout the

Presentation / Abstract • Phase 3Oral presentation Tue, May 26, 2026, 8:30 AM EEST

Arrowhead Pharmaceuticals to Participate in Upcoming May 2026 Events

PASADENA, Calif. --(BUSINESS WIRE)--May 4, 2026-- Arrowhead Pharmaceuticals, Inc. (NASDAQ: ARWR) today announced that it is scheduled to participate in the following upcoming events: BofA Securities 2026 Healthcare Conference – May 12-14, 2026 Type: Investor Group Dinner Date/Time: May 12, 2026

Presentation / Abstract

Arrowhead Pharmaceuticals Receives Positive CHMP Opinion Recommending Approval of REDEMPLO® (plozasiran) to Reduce Triglycerides in Adults with Familial Chylomicronemia Syndrome (FCS) in Europe

– If confirmed by the European Commission, REDEMPLO would be the first and only siRNA medicine authorized in the EU for both genetically confirmed and clinically diagnosed adult patients with FCS – People living with FCS have extremely high triglyceride levels and a substantially higher risk of

Arrowhead Pharmaceuticals to Webcast Fiscal 2026 Second Quarter Results

PASADENA, Calif. --(BUSINESS WIRE)--Apr. 20, 2026-- Arrowhead Pharmaceuticals, Inc. (NASDAQ: ARWR) today announced that it will host a webcast and conference call on May 7, 2026, at 4:30 p.m. ET to discuss its financial results for the fiscal 2026 second quarter ended March 31, 2026.

Arrowhead Pharmaceuticals Presents New Long-Term Efficacy and Safety Data for Plozasiran Across a Spectrum of Hypertriglyceridemia at the American College of Cardiology’s 75th Annual Scientific Session and Expo

– Patients with severe hypertriglyceridemia (sHTG) achieved an 83% median reduction in triglycerides (TG), with 96% of patients achieving TG levels below 500 mg/dL, a threshold associated with increased risk of acute pancreatitis – No adjudicated acute pancreatitis events occurred in any patient

Presentation / Abstract • Phase 2
Arrowhead Pharmaceuticals, Inc. • Endpoint Arena