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Lexicon Pharmaceuticals, Inc.

Pipeline3 assets

  • SotagliflozinINPEFA / ZYNQUISTA / SGLT1 / SGLT2 / Small Molecule / Cardiometabolic
    Heart FailureApprovedactiveUnited StatesHypertrophic Cardiomyopathy (HCM)Phase 3activeGlobalType 1 Diabetes (T1D)RegistrationactiveUnited States
  • PilavapadinLX9211 / AAK1 / Small Molecule / Pain / Neurology
    Diabetic Peripheral Neuropathic Pain (DPNP)Phase 2bactiveUnited StatesPostherpetic Neuralgia (PHN)Phase 2inactiveUnited States
  • LX9851LX9851 / ACSL5 / Small Molecule / Metabolism
    Obesity / Weight ManagementPhase 1activeGlobal

Latest news16 items

All news

Lexicon Pharmaceuticals Completes Enrollment of Pivotal Phase 3 SONATA-HCM Study of Sotagliflozin in Symptomatic Non-Obstructive and Obstructive Hypertrophic Cardiomyopathy (HCM)

Study substantially exceeded enrollment target of 500 patients Topline results anticipated in Q1 2027 THE WOODLANDS, Texas, July 27, 2026 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) today announced that randomization of patients has been completed in the pivotal Phase 3 “ SO

Enrollment • Phase 3Enrollment milestone Mon, Jul 27, 2026

Lexicon to Present Data at the American Diabetes Association (ADA) 2026 Scientific Sessions

Presentations highlight consistent A1c reductions with sotagliflozin in type 1 diabetes and pharmacokinetics of pilavapadin across renal function groups THE WOODLANDS, Texas, June 03, 2026 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) today announced that it will present data

Presentation / Abstract • Phase 1Poster presentation Sun, Jun 7, 2026, 12:30 PM CEST

Lexicon to Present Data at the American Academy of Neurology (AAN) Annual Meeting

Oral presentation highlights additional data from PROGRESS Phase 2b study of pilavapadin supporting selection of 10mg as optimal dose for Phase 3 development in DPNP New data on spasticity further validates the broader potential importance of the AAK1 pathway in neurologic diseases THE WOODLANDS,

Presentation / Abstract • Phase 2

Lexicon to Present Data on Effect of Kidney Function on the Long-term Efficacy and Safety of Sotagliflozin in Patients with Type 1 Diabetes at 19th International Conference on Advanced Technologies & Treatments for Diabetes

Post hoc data analysis concluded that sotagliflozin, a dual SGLT1 and SGLT2 inhibitor, improved glycemic control after one year in patients with normal and mildly reduced kidney function THE WOODLANDS, Texas, March 11, 2026 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc.

Presentation / Abstract
Lexicon Pharmaceuticals, Inc. • Endpoint Arena