Company profile
Spyre Therapeutics, Inc. logo

Spyre Therapeutics, Inc.

Pipeline7 assets

  • SPY001SPY001 / α4β7 / Monoclonal antibody / Gastroenterology
    Inflammatory Bowel Disease (IBD)Ulcerative Colitis
  • SPY002SPY002 / TL1A / Monoclonal antibody / Gastroenterology / Rheumatology
    Inflammatory Bowel Disease (IBD)Rheumatoid Arthritis (RA)
  • SPY003SPY003 / IL-23 / Monoclonal antibody / Gastroenterology
    Inflammatory Bowel Disease (IBD)
  • SPY120SPY120 / α4β7 + TL1A / Combination / Gastroenterology
    Inflammatory Bowel Disease (IBD)
  • SPY130SPY130 / α4β7 + IL-23 / Combination / Gastroenterology
    Inflammatory Bowel Disease (IBD)
  • SPY230SPY230 / TL1A + IL-23 / Combination / Gastroenterology
    Inflammatory Bowel Disease (IBD)Ulcerative Colitis
  • SPY072SPY072 / TL1A / Monoclonal antibody / Rheumatology
    Rheumatoid Arthritis (RA)Psoriatic Arthritis (PsA)Axial Spondyloarthritis (axSpA)

Latest news13 items

All news

Spyre Therapeutics to Participate in Upcoming June Investor Conferences

WALTHAM, Mass., May 26, 2026 (GLOBE NEWSWIRE) -- Spyre Therapeutics, Inc. (NASDAQ: SYRE), a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease (“IBD”) and rheumatic diseases, today

Spyre Therapeutics Announces Grants of Inducement Awards

WALTHAM, Mass., May 01, 2026 (GLOBE NEWSWIRE) -- Spyre Therapeutics, Inc. (NASDAQ: SYRE) (the “Company” or “Spyre”), a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease and rheumatic

Spyre Therapeutics Announces Proposed Public Offering of its Common Stock

WALTHAM, Mass., April 13, 2026 (GLOBE NEWSWIRE) -- Spyre Therapeutics, Inc. (“Spyre” or the “Company”) (Nasdaq: SYRE), a clinical-stage biotechnology company advancing best-in-class antibody engineering, dose optimization, and rational therapeutic combinations for the treatment of Inflammatory

Spyre Therapeutics Announces Grants of Inducement Awards

WALTHAM, Mass., April 03, 2026 (GLOBE NEWSWIRE) -- Spyre Therapeutics, Inc. (NASDAQ: SYRE) (the “Company” or “Spyre”), a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease and rheumatic

Spyre Therapeutics Announces Grants of Inducement Awards

WALTHAM, Mass., March 06, 2026 (GLOBE NEWSWIRE) -- Spyre Therapeutics, Inc. (NASDAQ: SYRE) (the “Company” or “Spyre”), a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease and rheumatic

Spyre Therapeutics to Participate in Upcoming March Investor Conferences

WALTHAM, Mass., Feb. 24, 2026 (GLOBE NEWSWIRE) -- Spyre Therapeutics, Inc. (NASDAQ: SYRE), a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease (“IBD”) and rheumatic diseases, today