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Taysha Gene Therapies, Inc.

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Taysha Gene Therapies Announces Multiple Presentations Highlighting its TSHA-102 Clinical Program at the 2026 IRSF Rett Syndrome Scientific Meeting

Recently disclosed longer-term REVEAL Part A data demonstrated broad, multi-domain functional impact that deepened over time through ≥12 months post-TSHA-102 regardless of age or disease severity Rett syndrome natural history data analysis shows a clear developmental plateau after 6 years of age,

Presentation / Abstract • Phase 1/2IRSF Rett Syndrome Scientific Meeting poster presentation Mon, Jun 29, 2026, 3:10 PM CT

Taysha Gene Therapies Announces Completion of Dosing in REVEAL Pivotal Trial and Reports Longer-Term Clinical Data from Part A of REVEAL Phase 1/2 Trials Evaluating TSHA-102 for Rett Syndrome

Completed dosing of 17 patients in REVEAL pivotal trial; topline data from 6 ‑ month interim analysis and FDA feedback on next steps toward BLA submission pathway expected 1H 2027 TSHA-102 was generally well-tolerated with no treatment-related SAEs or DLTs reported as of the June 2026 data cutoff

Interim Data • Phase 1/2Results call Mon, Jun 22, 2026, 8:30 AM ET
Taysha Gene Therapies, Inc. • Endpoint Arena