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Xencor, Inc.

Pipeline9 assets

  • XmAb819XmAb819 / ENPP3 x CD3 / Bispecific Antibody / Oncology
    Clear Cell Renal Cell Carcinoma (ccRCC)Phase 1ActiveGlobalColorectal Cancer (CRC)Phase 1ActiveGlobalNon-Small Cell Lung Cancer (NSCLC)Phase 1ActiveGlobal
  • XmAb541XmAb541 / CLDN6 x CD3 / Bispecific Antibody / Oncology
    Ovarian CancerPhase 1ActiveGlobalGerm Cell Tumors (GCT)Phase 1ActiveGlobalSolid TumorsPhase 1ActiveGlobal
  • XmAb808XmAb808 / B7-H3 x CD28 / Bispecific Antibody / Oncology
    Prostate Cancer / Solid TumorsPhase 1ActiveGlobal
  • XmAb942XmAb942 / TL1A / Monoclonal Antibody / Immunology
    Ulcerative Colitis (UC)Phase 2ActiveGlobalInflammatory Bowel Disease (IBD)Phase 2ActiveGlobal
  • XmAb412XmAb412 / TL1A x IL23p19 / Bispecific Antibody / Immunology
    Inflammatory Bowel Disease (IBD)Phase 1ActiveGlobal
  • PlamotamabCD20 x CD3 / Bispecific Antibody / Immunology
    Rheumatoid ArthritisPhase 1ActiveGlobal
  • XmAb657XmAb657 / CD19 x CD3 / Bispecific Antibody / Immunology
    Idiopathic Inflammatory MyositisPhase 1ActiveGlobal
  • ObexelimabCD19 x FcγRIIb / Monoclonal Antibody / Immunology
    Autoimmune DiseasesPhase 3ActiveGlobal
  • TobevibartHepatitis B Virus / Monoclonal Antibody / Infectious Disease
    Chronic Hepatitis B / Hepatitis DPhase 3ActiveGlobal

Latest news6 items

All news

Xencor Reports Second Quarter 2026 Financial Results

-- XmAb819 ccRCC expansion cohorts to be presented in an oral session at ESMO 2026; multiple Phase 1 sub-studies in earlier lines of therapy and additional indications now open for enrollment or planned -- -- XmAb942 enrollment in XENITH-UC remains on track with primary endpoint of the 12-week

Presentation / Abstract • Phase 1ESMO oral presentation Fri, Oct 23, 2026

Xencor Announces Proffered Paper Oral Presentation at ESMO 2026 for Phase 1 Clinical Study of XmAb819 in Advanced Clear Cell Renal Cell Carcinoma

-- ESMO presentation to highlight expansion-cohort results for IV doses evaluated for recommended Phase 3 dose -- -- Pivotal study of XmAb819 monotherapy in advanced ccRCC, planned to begin in 2027 -- PASADENA, Calif. --(BUSINESS WIRE)--Jul. 17, 2026-- Xencor, Inc.

Presentation / Abstract • Phase 1ESMO abstract release Sun, Oct 18, 2026, 3:05 PM PDT

Xencor Reports First Quarter 2026 Financial Results

-- XmAb819 clear cell renal cell carcinoma (ccRCC) expansion cohort results to be presented at a medical conference in 2H26 -- -- XmAb412 (TL1A x IL23p19) first-in-human healthy participant study on-track for 3Q26 start -- -- Plamotamab and XmAb657 autoimmune studies on-track for 2H26 progress

Xencor to Host Webcast to Discuss XmAb942 and XmAb412 Data Presentations at DDW

-- Data support potentially best-in-class profile of XmAb942, under evaluation in ongoing global Phase 2b XENITH-UC study on track for 12-week induction results in 2027 -- -- Novel XenLock™ format optimizes bispecifics for treatment of autoimmune diseases; first XenLock™ candidate XmAb412

Results Call • Phase 1

Xencor Announces Change to Ultomiris® Royalty Revenue Forecast

PASADENA, Calif. --(BUSINESS WIRE)--Mar. 4, 2026-- Xencor, Inc. (NASDAQ:XNCR), a clinical-stage biopharmaceutical company developing engineered antibodies for the treatment of cancer and autoimmune diseases, today announced that Alexion Pharmaceuticals, Inc. (the “Licensee”) informed Xencor, Inc.

Xencor, Inc. • Endpoint Arena