Vabysmofaricimab-svoa / VABYSMO / VEGF/Ang-2 / Bispecific antibody / Ophthalmology Neovascular age-related macular degeneration (nAMD) and Diabetic macular edema (DME)Approvedapproved
Ojemdatovorafenib / OJEMDA / Oncology Oncology (undisclosed approved indication)Approvedapproved
Miplyffaarimoclomol / MIPLYFFA / Rare Diseases / Neurology Niemann-Pick disease type C (NPC)ApprovedapprovedUS
Xaciatoclindamycin phosphate vaginal gel 2% / XACIATO / Small molecule / Gynecology / Infectious Disease Bacterial VaginosisApprovedapproved
Ixinitycoagulation factor IX (recombinant) / IXINITY / Factor IX / Recombinant protein / Hematology Hemophilia BApprovedapproved
Dsuviasufentanil sublingual tablet / DSUVIA / Opioid receptor / Small molecule / Pain Management PainApprovedapproved
Dare to Playsildenafil cream / DARE to PLAY / PDE5 / Small molecule / Gynecology / Sexual Health Female Sexual Arousal DisorderApprovedapproved
ersodetugRZ358 / INSR / Antibody / Metabolic Disorders Hypoglycemia due to congenital hyperinsulinism (cHI)Phase 3ongoingHypoglycemia due to tumor hyperinsulinismPhase 3ongoing
RZ402RZ402 / Ophthalmology Diabetic macular edema (DME)Phase 2ongoing
D-FiFCX-007 / Gene Therapy / Dermatology / Rare Diseases Dystrophic epidermolysis bullosa (DEB)Phase 3ongoing
seralutinibGB002 / PDGFR, CSF1R, and c-KIT / Inhaled tyrosine kinase inhibitor / Respiratory / Cardiovascular Pulmonary arterial hypertension (PAH)Phase 3ongoingPulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)Phase 2ongoing
cetrelimabJNJ-63723283 / PD-1 / Antibody / Oncology / Infectious Disease Muscle-invasive bladder cancer (MIBC)Phase 2ongoingChronic Hepatitis B Virus InfectionPhase 2ongoing
volixibatLUM-002 / Ileal bile acid transporter (IBAT) / Small molecule / Gastroenterology Primary sclerosing cholangitis (PSC)Phase 2bongoingPrimary biliary cholangitis (PBC)Phase 2ongoing
Major depressive disorderPhase 3ongoing
OHB-607OHB-607 / Recombinant human IGF-I/IGFBP-3 / Recombinant protein / Respiratory / Neonatology Prevention of bronchopulmonary dysplasia in extremely premature infantsPhase 2ongoing
REC-4881REC-4881 / Allosteric MEK1/2 / Small molecule / Oncology Familial adenomatous polyposisPhase 2ongoing
NIS793NIS793 / Antibody / Oncology Solid tumorsPhase 3ongoing
Cutaneous venous malformationsPhase 3ongoingClinically significant angiokeratomasPhase 2ongoing