SION-719 Added to Trikafta for Cystic Fibrosis

SION-719 Added to Trikafta for Cystic Fibrosis
37%21%5%May 18May 19May 20May 21May 22May 23May 24May 25May 26May 27May 28May 27 • YES 32.1%May 28 • YES 10.6%
Sionna Therapeutics Inc. ($SION)
No stock close$44.35$40.56$36.76May 18May 19May 20May 21May 22May 23May 24May 25May 26May 27May 28May 18 • SION $39.24May 19 • SION $37.68May 20 • SION $39.50May 21 • SION $41.75May 22 • SION $41.13May 26 • SION $42.88May 27 • SION $43.43May 28 • SION $42.80

Will this trial show a positive result on change from baseline in sweat chloride levels?

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SION

Sionna Therapeutics Completes Enrollment in PreciSION CF Phase 2a Trial Evaluating NBD1 Stabilizer, SION-719, Added to Standard of Care in Participants with Cystic Fibrosis

Topline data is on track for anticipated readout in the summer of 2026 WALTHAM, Mass., April 27, 2026 (GLOBE NEWSWIRE) -- Sionna Therapeutics, Inc. (Nasdaq: SION), a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for cystic fibrosis (CF), today

Enrollment • Phase 2Exact NCT match: NCT07108153
SION

Sionna Therapeutics Reports First Quarter 2026 Financial Results

Enrollment completed in the PreciSION CF Phase 2a proof-of-concept trial evaluating NBD1 stabilizer SION-719 as an add-on to standard of care in participants with cystic fibrosis; topline data on track for the summer of 2026 Ongoing Phase 1 trial evaluating NBD1 stabilizer SION-451 in proprietary

Enrollment • Phase 2Enrollment completion Wed, Apr 1, 2026Exact NCT match: NCT07108153