Fianlimab/cemiplimab for melanoma (HARMONY)
Will this trial show a positive result on objective response rate (ORROutcome measureObjective Response Rate (ORR)Objective response rate is the share of patients whose tumors shrink by a predefined amount. It is useful for early signals and accelerated approval settings, but it is more surrogate than survival outcomes.Primary outcome | Up to 72 monthsClinicalTrials.gov outcome) per Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1 based on blinded independent central review (BICR)?
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Advanced Melanoma
Melanoma is a cancer of pigment-making cells that can spread from the skin to distant organs. The main endpoint counts patients whose tumors shrink or disappear, indicating whether treatment is controlling the cancer.