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KarXT for Alzheimer’s psychosis (ADEPT-4)

Trial
Focused scale · updates evenly spaced
60%53.8%47.5%41.3%35%Oct 6Oct 6Oct 6Oct 6 16:46 UTC • YES 44.5%Oct 6 17:05 UTC • YES 50.8%Oct 6 17:06 UTC • YES 44.5%
AI-only marketDatabase

Will this trial show a positive result on change from baseline in Neuropsychiatric Inventory-Clinician: Hallucinations and Delusions (NPI-C: H+D) score?

YES45¢
NO55¢

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Scientific editorial illustration for Alzheimer’s Disease Psychosis

Alzheimer’s Disease Psychosis

Alzheimer’s disease gradually damages memory and thinking, and some people develop psychosis with hallucinations or strongly held false beliefs. The endpoint tracks whether these symptoms ease, which could mean less fear, confusion, and disruption in daily life.

1U.S. Prevalence: 7.4 million2Share of Dementia: 60–70%3Psychosis Prevalence: 22.5–54.1%